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1

Cyclodextrin Drug Carrier Systems

Uekama, Kaneto, Hirayama, Fumitoshi, Irie, Tetsumi

Journal:

Chemical Reviews

Year:

1998

Language:

english

File:

PDF, 324 KB

english, 1998

2

Potential Use of a Megamolecular Polysaccharide Sacran as a Hydrogel-Based Sustained Release System

Motoyama, Keiichi, Tanida, Yuki, Hata, Kyona, Hayashi, Tomoya, Higashi, Taishi, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Kaneko, Shinichiro, Arima, Hidetoshi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

3

Anti-inflammatory Effects of Novel Polysaccharide Sacran Extracted from Cyanobacterium Aphanothece sacrum in Various Inflammatory Animal Models

Motoyama, Keiichi, Tanida, Yuki, Hata, Kyona, Hayashi, Tomoya, Hashim, Irhan Ibrahim Abu, Higashi, Taishi, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Kaneko, Shinichiro, Arima, Hidetoshi

Year:

2016

Language:

english

File:

PDF, 2.04 MB

english, 2016

4

Enhancement of the Antiinflammatory Effect of Ethyl 4-Biphenylyl Acetate in Ointment by β-Cyclodextrin Derivatives: Increased Absorption and Localized Activation of the Prodrug in Rats

Hidetoshi Arima, Hirotoshi Adachi, Tetsumi Irie, Kaneto Uekama, Josef Pitha

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 858 KB

1990

5

WITHDRAWN: Antiulcerative effect of sacran on indomethacin-induced gastric ulcer in mice

Hayashi, Tomoya, Abe, Yuya, Kaneko, Shinichiro, Otsuka, Takayuki, Sato, Kiyoaki, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Higashi, Taishi, Motoyama, Keiichi, Arima, Hidetoshi

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 500 KB

english, 2015

6

Enhanced rectal absorption and reduced local irritation of the anti-inflammatory drug ethyl 4-biphenylylacetate in rats by complexation with water-soluble β-cyclodextrin derivatives and formulation as oleaginous suppository

Hidetoshi Arima, Takashi Kondo, Tetsumi Irie, Kaneto Uekama

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 725 KB

english, 1992

7

Enhancing effect of hydroxypropyl-β-cyclodextrin on cutaneous penetration and activation of ethyl 4-biphenylyl acetate in hairless mouse skin

Hidetoshi Arima, Tatsuaki Miyaji, Tetsumi Irie, Fumitoshi Hirayama, Kaneto Uekama

Journal:

European Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 765 KB

english, 1998

8

Drug solubilizers to aid pharmacologists: Amorphous cyclodextrin derivatives

Josef Pitha, Tetsumi Irie, Pamela B. Sklar, Jeffrey S. Nye

Journal:

Year:

1988

Language:

english

File:

PDF, 814 KB

english, 1988

9

Modification of rectal absorption of morphine from hollow-type suppositories with a combination of α-cyclodextrin and viscosity-enhancing polysaccharide

Kaneto Uekama, Takashi Kondo, Kiyotomo Nakamura, Tetsumi Irie, Katsumasa Arakawa, Masaoki Shibuya, Joji Tanaka

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 819 KB

english, 1995

10

Improvement of nasal bioavailability of luteinizing hormone-releasing hormone agonist, buserelin, by cyclodextrin derivatives in rats

Kazutaka Matsubara, Kazuya Abe, Tetsumi Irie, Kaneto Uekama

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 762 KB

english, 1995

11

Feasibility study of cyclodextrins as active pharmaceutical ingredients for the treatment of GM1-gangliosidosis

Maeda, Yuki, Motoyama, Keiichi, Higashi, Taishi, Horikoshi, Yuka, Takeo, Toru, Nakagata, Naomi, Kurauchi, Yuki, Katsuki, Hiroshi, Kondo, Yuki, Ishitsuka, Yoichi, Irie, Tetsumi, Era, Takumi, Arima, Hid

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 321 KB

english, 2016

12

Effects of α1-Acid Glycoprotein on Erythrocyte Deformability and Membrane Stabilization

Matsumoto, Kazuaki, Nishi, Katsuhide, Tokutomi, Yoshiko, Irie, Tetsumi, Suenaga, Ayaka, Otagiri, Masaki

Journal:

Biological & Pharmaceutical Bulletin

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

13

Preventive Effect of Tranilast on Oleic Acid-Induced Lung Injury in Guinea Pigs

Ishitsuka, Yoichi, Moriuchi, Hiroshi, Yang, Changqing, Kurita, Sumika, Golbidi, Saeid, Irikura, Mitsuru, Irie, Tetsumi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

14

Impact of the Niemann–Pick c1 Gene Mutation on the Total Cellular Glycomics of CHO Cells

Furukawa, Jun-ichi, Soga, Minami, Okada, Kazue, Yokota, Ikuko, Piao, Jinhua, Irie, Tetsumi, Era, Takumi, Shinohara, Yasuro

Journal:

Journal of Proteome Research

Year:

2017

Language:

english

File:

PDF, 939 KB

english, 2017

15

Improvement of Subcutaneous Bioavailability of Insulin by Sulphobutyl Ether β-Cyclodextrin in Rats

KEIICHI TOKIHIRO, HIDETOSHI ARIMA, SHINICHIROU TAJIRI, TETSUMI IRIE, FUMITOSHI HIRAYAMA, KANETO UEKAMA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

16

Prolongation of Intrathecal and Sciatic Nerve Blocks Using a Complex of Levobupivacaine with Maltosyl-??-Cyclodextrin in Rats

Karashima, Ken, Taniguchi, Masahiko, Nakamura, Tadashi, Takasaki, Mayumi, Matsuo, Kanako, Irikura, Mitsuru, Irie, Tetsumi

Journal:

Anesthesia & Analgesia

Year:

2007

Language:

english

File:

PDF, 477 KB

english, 2007

17

PARTICIPATION OF CYCLODEXTRIN INCLUSION CATALYSIS IN PHOTOLYSIS OF CHLORPROMAZINE TO GIVE PROMAZINE IN AQUEOUS SOLUTION

Uekama, Kaneto, Irie, Tetsumi, Hirayama, Fumitoshi

Journal:

Chemistry Letters

Year:

1978

Language:

english

File:

PDF, 5.82 MB

english, 1978

18

Protective effects of cyclodextrins on drug-induced hemolysis in vitro.

UEKAMA, KANETO, IRIE, TETSUMI, SUNADA, MIKI, OTAGIRI, MASAKI, TSUBAKI, KENICHI

Journal:

Journal of Pharmacobio-Dynamics

Year:

1981

File:

PDF, 452 KB

1981

19

Stabilization of Prostaglandin E1 in Fatty Alcohol Propylene Glycol Ointment by Acidic Cyclodextrin Derivative, O-Carboxymethyl-O-ethyl-.BETA.-cyclodextrin.

ADACHI, Hirotoshi, IRIE, Tetsumi, HARAYAMA, Fumitoshi, UEKAME, Kaneko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1992

File:

PDF, 906 KB

1992

20

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease

Maeda, Yuki, Motoyama, Keiichi, Nishiyama, Rena, Higashi, Taishi, Onodera, Risako, Nakamura, Hideaki, Takeo, Toru, Nakagata, Naomi, Yamada, Yusei, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Era, T

Journal:

Year:

2019

Language:

english

File:

PDF, 10.44 MB

english, 2019

21

In vitro transdermal permeation behavior of isosorbide dinitrate in the absence and presence of 2-hydroxypropyl-β-cyclodextrin: solutions and suspensions

Zao, Katsutoshi, Ishiguro, Takako, Iohara, Daisuke, Anraku, Makoto, Seo, Hakaru, Irie, Tetsumi, Uekama, Kaneto, Hirayama, Fumitoshi

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

2019

Language:

english

File:

PDF, 1020 KB

english, 2019

22

Improvement in percutaneous absorption of prednisolone by .BETA.- and .GAMMA.-cyclodextrin complexations.

UEKAMA, KANETO, ARIMORI, KAZUHIKO, SAKAI, ATSUSHI, MASAKI, KATSUHIRO, IRIE, TETSUMI, OTAGIRI, MASAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 537 KB

english, 1987

23

Role of 6- O -α-maltosyl-β-cyclodextrin in lysosomal cholesterol deprivation in Npc1- deficient Chinese hamster ovary cells

Okada, Yasuyo, Ueda, Erika, Kondo, Yuki, Ishitsuka, Yoichi, Irie, Tetsumi, Higashi, Taishi, Motoyama, Keiichi, Arima, Hidetoshi, Matuso, Muneaki, Higaki, Katsumi, Ohno, Kousaku, Nishikawa, Junichi, Ic

Journal:

Carbohydrate Research

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

24

Amorphous Water-Soluble Cyclodextrin Derivatives: 2-Hydroxyethyl, 3-Hydroxypropyl, 2-Hydroxyisobutyl, and Carboxamidomethyl Derivatives of β-Cyclodextrin

Tetsumi Irie, Kazuhiro Fukunaga, Atsuya Yoshida, Kaneto Uekama, Henry M. Fales, Josef Pitha

Journal:

Pharmaceutical Research

Year:

1988

File:

PDF, 694 KB

1988

25

Mass Spectroscopic Evidence on Inhibiting Effect of Maltosyl–β-Cyclodextrin on Insulin Self-association

Keiichi Tokihiro, Tetsumi Irie, Fumitoshi Hirayama, Kaneto Uekama

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 352 KB

english, 1996

26

Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats

Daisuke Kadowaki, Satomi Sumikawa, Kanami Arimizu, Kazuaki Taguchi, Kenichiro Kitamura, Yoichi Ishitsuka, Yuki Narita, Tetsumi Irie, Victor Tuan Giam Chuang, Toru Maruyama, Masaki Otagiri, Sumio Hirat

Journal:

Year:

2012

Language:

english

File:

PDF, 489 KB

english, 2012

27

Differences in the enhancing effects of water soluble β-cyclodextrins on the release of ethyl 4-biphenylyl acetate, an anti-inflammatory agent from an oleaginous suppository base

Arima, Hidetoshi, Irie, Tetsumi, Uekama, Kaneto

Journal:

International Journal of Pharmaceutics

Year:

1989

Language:

english

File:

PDF, 659 KB

english, 1989

28

Preparation of hydrophilic C60(OH)10/2-hydroxypropyl-β-cyclodextrin nanoparticles for the treatment of a liver injury induced by an overdose of acetaminophen

Umezaki, Yoshitaka, Iohara, Daisuke, Anraku, Makoto, Ishitsuka, Yoichi, Irie, Tetsumi, Uekama, Kaneto, Hirayama, Fumitoshi

Journal:

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

29

Oxidative Stress in Early Stage of Acute Lung Injury Induced with Oleic Acid in Guinea Pigs

Yang, Changqing, Moriuchi, Hiroshi, Takase, Junko, Ishitsuka, Yoichi, Irikura, Mitsuru, Irie, Tetsumi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2003

Language:

english

File:

PDF, 79 KB

english, 2003

30

Fertility of cold-stored mouse sperm is recovered by promoting acrosome reaction and hyperactivation after cholesterol efflux by methyl-beta-cyclodextrin

Yoshimoto, Hidetaka, Takeo, Toru, Irie, Tetsumi, Nakagata, Naomi

Journal:

Biology of Reproduction

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

31

Comparative studies of the enhancing effects of cyclodextrins on the solubility and oral bioavailability of tacrolimus in rats

Hidetoshi Arima, Kiyokazu Yunomae, Kouzou Miyake, Tetsumi Irie, Fumitoshi Hirayama, Kaneto Uekama

Journal:

Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 229 KB

english, 2001

32

Comparative effects of respiratory stimulants on hypoxic neuronal cell injury in SH-SY5Y cells and in hippocampal slice cultures from rat pups

Tanaka, Kaori, Ishitsuka, Yoichi, Kurauchi, Yuki, Yamaguchi, Keitaro, Kadowaki, Daisuke, Irikura, Mitsuru, Katsuki, Hiroshi, Irie, Tetsumi

Journal:

Pediatrics International

Year:

2013

Language:

english

File:

PDF, 719 KB

english, 2013

33

Some pharmaceutical properties of 3-hydroxypropyl- and 2,3-dihydroxypropyl-.BETA.-cyclodextrins and their solubilizing and stabilizing abilities.

YOSHIDA, Atsuya, YAMAMOTO, Masanobu, IRIE, Tetsumi, HIRAYAMA, Fumitoshi, UEKAMA, Kaneto

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 744 KB

1989

34

A Selective Thromboxane A2 (TXA2) Synthase Inhibitor, Ozagrel, Attenuates Lung Injury and Decreases Monocyte Chemoattractant Protein-1 and Interleukin-8 mRNA Expression in Oleic Acid–Induced Lung Injury in Guinea Pigs

Ishitsuka, Yoichi, Moriuchi, Hiroshi, Isohama, Yoichiro, Tokunaga, Hidehiro, Hatamoto, Keita, Kurita, Sumika, Irikura, Mitsuru, Iyama, Ken-ichi, Irie, Tetsumi

Journal:

Journal of Pharmacological Sciences

Year:

2009

Language:

english

File:

PDF, 347 KB

english, 2009

35

Knowledge and awareness of nonpharmacist salespersons regarding over-the-counter drug use in patients with chronic kidney disease in Japan

Kondo, Yuki, Ishitsuka, Yoichi, Kawabata, Nobuhiro, Iwamoto, Nobuhide, Takahashi, Risa, Narita, Yuki, Kadowaki, Daisuke, Hirata, Sumio, Uchino, Satoru, Irie, Tetsumi, Jha, Vivekanand

Journal:

Year:

2019

Language:

english

File:

PDF, 797 KB

english, 2019

36

Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey

Kondo, Yuki, Ishitsuka, Yoichi, Shigemori, Eri, Irikura, Mitsuru, Kadowaki, Daisuke, Hirata, Sumio, Maemura, Takeshi, Irie, Tetsumi

Journal:

BMC Health Services Research

Year:

2014

Language:

english

File:

PDF, 299 KB

english, 2014

37

Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients

Maeda, Yuki, Motoyama, Keiichi, Higashi, Taishi, Horikoshi, Yuka, Takeo, Toru, Nakagata, Naomi, Kurauchi, Yuki, Katsuki, Hiroshi, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Furuya, Hirokazu, Era,

Journal:

Journal of Pharmacy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

38

Enhanced Absorption of Cyclosporin A by Complexation with Dimethyl-.BETA.-cyclodextrin in Bile Duct-Cannulated and -Noncannulated Rats.

MIYAKE, Kouzou, ARIMA, Hidetoshi, IRIE, Tetsumi, HIRAYAMA, Fumitoshi, UEKAMA, Kaneto

Journal:

Biological & Pharmaceutical Bulletin

Year:

1999

File:

PDF, 1000 KB

1999

39

Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced by N -acetyl- p -benzoquinone imine

Nagatome, Minako, Kondo, Yuki, Kadowaki, Daisuke, Saishyo, Yusuke, Irikura, Mitsuru, Irie, Tetsumi, Ishitsuka, Yoichi

Journal:

Year:

2018

Language:

english

File:

PDF, 2.35 MB

english, 2018

40

Synthesis of multi-lactose-appended β-cyclodextrin and its cholesterol-lowering effects in Niemann–Pick type C disease-like HepG2 cells

Motoyama, Keiichi, Nishiyama, Rena, Maeda, Yuki, Higashi, Taishi, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Era, Takumi, Arima, Hidetoshi

Journal:

Beilstein Journal of Organic Chemistry

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

41

Evaluation of a new beta-adrenoceptor agonist, procaterol, based on metabolic responses in rats

Yuichi Saitoh, Yasuo Irie, Tetsumi Hosokawa, Takehiro Igawa, Fukuko Hashimura, Hideaki Kohri

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 617 KB

english, 1978

42

Differences in reaction specificity toward lipoprotein X and abnormal LDL among 6 homogeneous assays for LDL-cholesterol

Matsushima, Kazumi, Sugiuchi, Hiroyuki, Anraku, Kensaku, Nishimura, Hitoshi, Manabe, Masahiro, Ikeda, Katsuyoshi, Ando, Yukio, Kondo, Yuki, Ishitsuka, Yoichi, Irikura, Mitsuru, Irie, Tetsumi

Journal:

Clinica Chimica Acta

Year:

2015

Language:

english

File:

PDF, 876 KB

english, 2015

43

The tissue content of cyclic AMP in rats after microwave irradiation in vivo.

SAITOH, YUICHI, HOSOKAWA, TETSUMI, IGAWA, TAKEHIRO, IRIE, YASUO

Journal:

Journal of Pharmacobio-Dynamics

Year:

1980

File:

PDF, 628 KB

1980

44

Famotidine Orally Disintegrating Tablets: Bitterness Comparison of Original and Generic Products

Tokuyama, Emi, Matsunaga, Chiharu, Yoshida, Koichi, Mifsud, Jean-Christophe, Irie, Tetsumi, Yoshida, Miyako, Uchida, Takahiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2009

Language:

english

File:

PDF, 268 KB

english, 2009

45

ANDP-2, A Novel Acrinol Degradation Product by Light

Iijima, Tomonori, Tanaka, Teruo, Yoshioka, Toshimasa, Ichioka, Yuki, Hirano, Masashi, Nishiyama, Masami, Kido, Yutaka, Tanaka, Toshiharu, Irie, Tetsumi

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2007

Language:

english

File:

PDF, 224 KB

english, 2007

46

Utility of 2-hydroxypropyl-.BETA.-cyclodextrin in an intramuscular injectable preparation of nimodipine.

YOSHIDA, Atsuya, YAMAMOTO, Masanobu, ITOH, Takahiro, IRIE, Tetsumi, HIRAYAMA, Fumitoshi, UEKAMA, Kaneto

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 764 KB

1990

47

Possible Fnhancing Mechanism of the Cutaneous Permeation of 4-Biphenylylacetic Acid by .BETA.-Cyclodextrin Derivatives in Hydrophilic Ointment.

ARIMA, Hidetoshi, MIYAJI, Tatsuaki, IRIE, Tetsumi, HIRAYAMA, Fumitoshi, UEKAMA, Kaneto

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1996

File:

PDF, 791 KB

1996

48

Edoxaban Exerts Antioxidant Effects Through FXa Inhibition and Direct Radical-Scavenging Activity

Narita, Yuki, Hamamura, Kana, Kashiyama, Mami, Utsumi, Sara, Kakizoe, Yutaka, Kondo, Yuki, Ishitsuka, Yoichi, Jono, Hirofumi, Irie, Tetsumi, Mukoyama, Masashi, Saito, Hideyuki, Kadowaki, Daisuke, Hira

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.75 MB

english, 2019

49

Protection afforded by a herbal medicine, Sho-seiryu-to (TJ-19), against oleic acid-induced acute lung injury in guinea-pigs

Chang-qing Yang, Dr Yoichi Ishitsuka, Hiroshi Moriuchi, Saeid Golbidi, Zhen-ji Jin, Mitsuru Irikura, Tetsumi Irie

Journal:

Journal of Pharmacy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 1002 KB

english, 2009

50

New Perspectives in Cyclodextrin Pharmaceutical Applications

Kaneto Uekama,Tetsumi Irie

Journal:

Clinical Drug Investigation

Year:

1990

Language:

english

File:

PDF, 1.00 MB

english, 1990

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